IL-28B Antibody | 7479

IL-28B Antibody | 7479 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: N/A

Immunogen: IL-28B antibody was raised against a 17 amino acid peptide near the center of human IL-28B.
The immunogen is located within amino acids 120 - 170 of IL-28B .

Research Area: Innate Immunity

Tested Application: E, WB, IF

Application: IL-28B antibody can be used for detection of IL-28B by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: IL-28B antibody is human specific. IL-28B antibody may cross-react with IL-28A and IL-29.

Positive Control 1: Cat. No. 1201 - HeLa Cell Lysate

Positive Control 2: Cat. No. 17-001 - HeLa Cell Slide

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 20 kDa
Observed: 16kDa

Validation: N/A

Isoform: N/A

Purification: IL-28B Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: IL-28B Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: IL-28B antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: IL-28B Antibody : IL28B, IL28C, IL-28B, IL28B, ZCYTO22, Interferon lambda-3, Cytokine Zcyto22, IFN-lambda-3

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Interleukin 28 (IL-28B) , also known as interferon lambda 3, is cytokine distantly related to type I interferons and the IL-10 family (1) . The IL-28B gene and the closely related cytokine genes IL-28A and IL-29 form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection and can induce anti-viral activity (2, 3) . All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor-beta (IL10RB) and interleukin 28 receptor- alpha (IL28RA) (1) .