IL-37 (Human) ELISA Kit | E5065-100

IL-37 (Human) ELISA Kit | E5065-100

Description: Interleukin-37 (IL-37) belongs to the IL-1 family of cytokines which functions as a natural suppressor of inflammatory and immune responses. Immune and non-immune cells produce IL-37 precursor following pro-inflammatory stimuli. The IL-37 gene is in the human located on the long chromosome arm of chromosome 2. During inflammation, IL-37 restores the metabolism of the cell by reducing succinate, inhibiting mTOR, and activating AMPK. IL-37 levels are abnormal in patients with inflammatory and autoimmune diseases. ’s IL-37 (Human) ELISA Kit is used for the quantitative detection of IL-37 in serum, plasma, tissue homogenates and other biological fluids. It is based on the principle of sandwich ELISA. The capture antibody is pre-coated on 96-well plates. The standards, test samples and biotin conjugated detection antibody are added to the wells subsequently, and washed with wash buffer. HRP-Streptavidin is added and unbound congates are washed away with wash buffer. The HRP enzymatic reaction is detected using TMB-substrate. Finally, an acidic stop solution terminates the enzymatic reaction. The color developed is directly proportional to the amount of IL-37 in the sample.

Alternate Name: IL37 ELISA Kit; Interleukin-37 ELISA Kit; FIL1 zeta ELISA Kit; IL-1F7 ELISA Kit; FIL1 ELISA Kit; FIL1 ELISA Kit; ZETA ELISA Kit; FIL1Z ELISA Kit; IL1H4 ELISA Kit; IL1F7 ELISA Kit; IL-1H4 ELISA Kit; IL-1F7b ELISA Kit; IL-1H ELISA Kit; IL-1RP1 ELISA Kit; IL-1X protein ELISA Kit; IL1RP1 ELISA Kit; interleukin 1 family member 7 ELISA Kit; IL-1X ELISA Kit; interleukin 1 family ELISA Kit; member 7 ELISA Kit; zeta ELISA Kit; interleukin 1 ELISA Kit; zeta ELISA Kit; interleukin-1 family member 7 ELISA Kit; Interleukin-1 homolog 4 ELISA Kit; interleukin-1 superfamily z ELISA Kit; Interleukin-1 zeta ELISA Kit; Interleukin-1-related protein ELISA Kit

Tag Line: A highly sensitive sandwich ELISA kit for the quantitative measurement of IL-37

Summary: N/A

Detection Method: Absorbance is measured at 450 nm

Sample Type: Human Serum, Plasma, Tissue lysates and other biological fluids

Species Reactivity: Human

Applications: The ELISA kit is used for the quantitative detection of IL-37 in serum, plasma, tissue homogenates and other biological fluids

Features & Benefits: Sensitivity: 18.75 pg/ml Recovery Rate: 89-99% for serum, 85-101% for EDTA plasma and 92-104% for heparin plasma Detection range: 31.25-2000 pg/ml Assay Precision; Intra-Assay CV < 8% and Inter-Assay < 10% Highly sensitive and specific