IL-7, human recombinant | 4146

IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Human and murine IL-7 is cross-species reactive. Recombinant human IL-7 is a 17.4 kDa protein containing 153 amino acid residues.

4146 | IL-7 human recombinant DataSheet

Biomolecule/Target: IL-7

Synonyms: Lymphopoietin 1(LP-1), pre-B cell factor

Alternates names: BMP4, ZYME, BMP2B, BMP2B1

Taglines: A cytokine important for B and T cell development

NCBI Gene ID #: 652

NCBI Gene Symbol: BMP4

Gene Source: Human

Accession #: P12644

Recombinant: Yes

Source: Human 293 cell expressed

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: 98%

Assay #2: HPLC

Endotoxin Level: <0.1 ng/g

Activity (Specifications/test method): N/A

Biological activity: ED is typically 2 to 10 ng/mL. The specific activity was determined by the dose dependent induction of alkaline phosphatase production in the ATDC-5 cell line (Mouse chondrogenic cell line).

Results: 2 to 10 ng/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 34 kDa, homodimer, glycosylated.

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Lyophilized from 10 mM HoAc

Reconstitution Instructions: Reconstitute in sterile 4 mM HCl containing 0.1% endotoxin-free recombinant human serum albumin.

Amino acid sequence: N/A