Description
IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Human and murine IL-7 is cross-species reactive. Recombinant human IL-7 is a 17.4 kDa protein containing 153 amino acid residues.
4146 | IL-7 human recombinant DataSheet
Biomolecule/Target: IL-7
Synonyms: Lymphopoietin 1(LP-1), pre-B cell factor
Alternates names: BMP4, ZYME, BMP2B, BMP2B1
Taglines: A cytokine important for B and T cell development
NCBI Gene ID #: 652
NCBI Gene Symbol: BMP4
Gene Source: Human
Accession #: P12644
Recombinant: Yes
Source: Human 293 cell expressed
Purity by SDS-PAGEs: 95%
Assay: SDS-PAGE
Purity: 98%
Assay #2: HPLC
Endotoxin Level: <0.1 ng/g
Activity (Specifications/test method): N/A
Biological activity: ED is typically 2 to 10 ng/mL. The specific activity was determined by the dose dependent induction of alkaline phosphatase production in the ATDC-5 cell line (Mouse chondrogenic cell line).
Results: 2 to 10 ng/ml
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 34 kDa, homodimer, glycosylated.
Concentration: N/A
Appearance: Lyophilized protein
Physical form description: Lyophilized from 10 mM HoAc
Reconstitution Instructions: Reconstitute in sterile 4 mM HCl containing 0.1% endotoxin-free recombinant human serum albumin.
Amino acid sequence: N/A