Description
IL10RA Polyclonal Antibody | E-AB-13869 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: CD210, CDw210a, CDw210a antigen, HIL 10R, HIL10R, I10R1, IL 10R 1, IL 10R A, IL 10R, IL 10R1, IL-10 receptor subunit alpha, IL-10R subunit 1, IL-10R subunit alpha, IL-10R1, IL-10RA, IL10R, IL10R1, IL10RA, Interleukin 10 receptor alpha, Interleukin 10 receptor alpha chain, Interleukin-10 receptor subunit 1, Interleukin-10 receptor subunit alpha
Application: IHC, ELISA
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Immunology
Background: The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
Concentration: 0.6 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human IL10RA
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A