IL18, mouse recombinant | 7326

Interleukin 18 (IL-18), previously known as interferon-gamma (IFN-gamma)-inducing factor, is an activator of NK cells and a co-inducer of Th1 cytokines. IL-18 is produced from Kupffer cells, activated macrophages, keratinocytes, intestinal epithelial cells, osteoblasts, adrenal cortex cells and murine diencephalon. IL-18 was expressed in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

7326 | IL18, mouse recombinant DataSheet

Biomolecule/Target :IL18

Synonyms: IL-18, IFN-gamma-inducing factor (IGIF), Interleukin-1 gamma

Alternates names: IL-18, IFN-gamma-inducing factor (IGIF), Interleukin-1 gamma

Taglines: An activator of NK cells and a co-inducer of Th1 cytokines

NCBI Gene ID #: 16173

NCBI Gene Symbol: IL18

Gene Source: Mouse

Accession #: P70380

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGE: ≥90%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per 1 microgram of protein

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 20.4 kDa (178 aa, 36-192 aa + His Tag), confirmed by MALDI-TOF.

Concentration: 1 mg/ml

Appearance: Liquid

Physical form description: 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol.

Reconstitution Instructions: N/A

Amino acid sequence: MGSSHHHHHH SSGLVPRGSH MNFGRLHCTT AVIRNINDQV LFVDKRQPVF EDMTDIDQSA SEPQTRLIIY MYKDSEVRGL AVTLSVKDSK MSTLSCKNKI ISFEEMDPPE NIDDIQSDLI FFQKRVPGHN KMEFESSLYE GHFLACQKED DAFKLILKKK DENGDKSVMF TLTNLHQS

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans