Description
IL18R1 Antibody | 18-777 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 19-320 of human IL18R1 (NP_003846.1) .
Research Area: Chemokines & Cytokines, Immunology, Innate Immunity
Tested Application: WB, IF
Application: WB: 1:500 - 1:1000
IF: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: NCI-H460
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 75kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: CD218a, CDw218a, IL-1Rrp, IL18RA, IL1RRP, interleukin-18 receptor 1, CD218 antigen-like family member A, IL-18R-1, IL-18R-alpha, IL-18R1, IL-18Ralpha, IL1 receptor-related protein, IL18Ralpha2, IL1R-rp, cytokine receptor, interleukin-18 receptor alpha
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18) , and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2) , and IL1RL1 (T1/ST2) , form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.