IL1R2 Antibody | 15-356

IL1R2 Antibody | 15-356 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-320 of human IL1R2 (NP_775465.1) .

Research Area: Chemokines & Cytokines, Immunology, Innate Immunity, Stem Cell

Tested Application: WB, IF

Application: WB: 1:500 - 1:2000
IF: 1:50 - 1:100

Specificiy: N/A

Positive Control 1: SKOV3

Positive Control 2: Raji

Positive Control 3: DU145

Positive Control 4: HeLa

Positive Control 5: A-549

Positive Control 6: Mouse lung

Molecular Weight: Observed: 44kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: IL1R2, type II interleukin-1 receptor, beta, MGC47725, interleukin 1 receptor, type II, IL1RB, CD121b, antigen CDw121b

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A) , interleukin beta (IL1B) , and interleukin 1 receptor, type I (IL1R1/IL1RA) , and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage.