IL31 Antibody (N-term) [APR06163G]

IL31 Antibody (N-term) [APR06163G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This IL31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-40 amino acids from the N-terminal region of human IL31.

Cellular Localisation: Secreted.

Molecular Weight: 18205

Clone: Polyclonal

Gene Name: IL31

Gene ID: 386653

Function: Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR (PubMed:15184896) . May function in skin immunity (PubMed:15184896) . Enhances myeloid progenitor cell survival in vitro (By similarity) . Induces RETNLA and serum amyloid A protein expression in macrophages (By similarity) .

Summary: Tissue Location: Detected at low levels in testis, bone marrow, skeletal muscle, kidney, colon, thymus, small intestine and trachea

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: IHC-P, FC, WB

Dilution: WB--1:1000 IHC-P--1:100~500 FC--1:10~50

Synonyms: Interleukin-31, IL-31, IL31