Description
IL4 polyclonal Antibody | BS70684 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human
Application: WB IHC
Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200
Background: Interleukin-4 (IL-4), also designated B cell stimulatory factor-1, is a glycosylated cytokine secreted by activated T lymphocytes, basophils and mast cells. The secreted IL-4 protein promotes the growth and differentiation of cells that participate in immune defense by favoring such events as the expansion of the Th2 lineage relative to Th1 cells. These T helper cell subsets are defined by their pattern of cytokine secretion: Th1 cells secrete IL-2, TNFβ and IFN-γ, while Th2 cells secrete IL-4, IL-5 and IL-10. Another key immunological function of IL-4 is to induce immunoglobulin class switching. IL-4 has been shown to induce the production of IgE and enhance IgG4 secretion by B cells, but suppress the production of IgM, IgA, IgG1, IgG2, and IgG3.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IL4 polyclonal Antibody detects endogenous levels of IL4 protein.
Molecular Weight: ~ 17 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: BSF1; IL-4; BCGF1; BSF-1; BCGF-1;
Immunogen: Recombinant protein of human IL4.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: