ILKAP Antibody (Center) [APR16843G]

ILKAP Antibody (Center) [APR16843G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This ILKAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-122 amino acids from the Central region of human ILKAP.

Cellular Localisation: Cytoplasm.

Molecular Weight: 42907

Clone: Polyclonal

Gene Name: ILKAP

Gene ID: 80895

Function: Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling. Inhibits the ILK-GSK3B signaling axis and may play an important role in inhibiting oncogenic transformation.

Summary: Tissue Location: Widely expressed. Highest levels expressed in striated muscle. Much lower levels evident in various smooth muscle tissues.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Integrin-linked kinase-associated serine/threonine phosphatase 2C, ILKAP, ILKAP