Imiquimod | 1698

Cell-permeable. Topical immune response modifier that displays anti-angiogenic, anti-viral and anti-inflammatory properties. Up-regulates IL-18 and down-regulates MMP-9 through recognition of Toll-like receptor 7 (TLR7) and subsequent activation of MyD88-dependent pathway.

Imiquimod is a topical immune response modifier that displays anti-angiogenic, anti-viral and anti-inflammatory properties. Up-regulates IL-18 and down-regulates MMP-9 through recognition of Toll-like receptor 7 (TLR7) and subsequent activation of MyD88-dependent pathway.

1698 | Imiquimod DataSheet

Alternate Name/Synonyms: 1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine; R-837

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 99011-02-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₄H₁₆N₄

Molecular Weight: 240.3

Cell-Permeable?: Yes

Purity: ≥95% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A Toll-like receptor 7 (TLR-7) agonist

MDL Number: MFCD00866946

PubChem CID: 57469

SMILES: CC(C)CN1C=NC2=C1C3=CC=CC=C3N=C2N

InChi: InChI=1S/C14H16N4/c1-9(2)7-18-8-16-12-13(18)10-5-3-4-6-11(10)17-14(12) 15/h3-6,8-9H,7H2,1-2H3,(H2,15,17)

InChi Key: DOUYETYNHWVLEO-UHFFFAOYSA-N