Indole-3-carbinol | B2839

Indole-3-carbinol is an anticancer phytochemical in cruciferous vegetables. It is produced by the breakdown of the glucosinolate glucobrassicin by the action of enzyme myrosinase. It induces apoptosis in cancer cells. It inhibits NF-κB, Akt and MAPK signaling pathways. It inactivates a ubiquitin E3 ligase (WWP1), which restores the tumor suppressive activity of PTEN.

Indole-3-carbinol is an anticancer phytochemical in cruciferous vegetables. It is produced by the breakdown of the glucosinolate glucobrassicin by the action of enzyme myrosinase. It induces apoptosis in cancer cells. It inhibits NF-κB, Akt and MAPK signaling pathways. It inactivates a ubiquitin E3 ligase (WWP1), which restores the tumor suppressive activity of PTEN.

B2839 | Indole-3-carbinol DataSheet

Alternate Name/Synonyms: 3-Hydroxymethylindole, Indole-3-methanol, Indinol, 1H-Indole-3-methanol, 1H-indol-3-ylmethanol

Appearance: Crystalline solid

Formulation:

CAS Number: 700-06-1

Structure Available?: True

Peptide sequence:

Salt Form: False

Molecular Formula: C₉H₉NO

Molecular Weight: 147.17

Cell-Permeable?: True

Purity: ≥96%

Solubilities: 7 mg/ml in in Water, 3 mg/ml in in DMSO, 10 mg/ml in in Ethanol

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: Anticancer phytochemical in cruciferous vegetables

MDL Number: MFCD00005632

PubChem CID: 3712

SMILES: C1=CC=C2C(=C1)C(=CN2)CO

InChi: InChI=1S/C9H9NO/c11-6-7-5-10-9-4-2-1-3-8(7)9/h1-5,10-11H,6H2

InChi Key: IVYPNXXAYMYVSP-UHFFFAOYSA-N