ING-2 AM | B3137

ING-2 AM is the membrane permeable form of the sodium indicator ING-2 (Cat. No. B3138). Masking the negative charge using non-polar, ester-linked moieties (AM ester) allows the molecule to enter cells through passive diffusion. Once inside the cell, ubiquitous intracellular esterase enzymes promote rapid hydrolysis of the AM ester leaving the active, highly polar form of the indicator trapped inside the cell. ING-2 AM is compatible with spectrofluorimeters and fluorescence microscopy using common fluorescein, GFP or YFP filters.

ING-2 AM is the membrane permeable form of the sodium indicator ING-2 (Cat. No. B3138). Masking the negative charge using non-polar, ester-linked moieties (AM ester) allows the molecule to enter cells through passive diffusion. Once inside the cell, ubiquitous intracellular esterase enzymes promote rapid hydrolysis of the AM ester leaving the active, highly polar form of the indicator trapped inside the cell. ING-2 AM is compatible with spectrofluorimeters and fluorescence microscopy using common fluorescein, GFP or YFP filters.

B3137 | ING-2 AM DataSheet

Alternate Name/Synonyms: Sodium (Na⁺) indicator; ING-2 membrane permeable; ING-2 acetoxymethyl ester; Fluorescent Sodium Na⁺ indicator

Appearance: Orange powder

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Structure Available?: TRUE

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Molecular Formula: C₅₃H₆₀Cl₂N₂O₁₈

Molecular Weight: 1084

Cell-Permeable?: TRUE

Purity: ≥ 90%

Solubilities: ~2 mg/ml in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A membrane permeable fluorescent sodium indicator

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