INHBA Polyclonal Antibody | E-AB-15512

INHBA Polyclonal Antibody | E-AB-15512 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Activin beta-A chain, EDF, Erythroid differentiation factor, Erythroid differentiation protein, Follicle stimulating hormone releasing protein, FRP, FSH releasing protein, INHBA, INHBA, Inhibin beta A chain, Inhibin beta A subunit, Inhibin, beta 1, Inhibin, beta A (activin A, activin AB alpha polypeptide)

Application: WB, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Signal Transduction

Background: The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.

Concentration: 0.6 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human INHBA

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:1000-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 47 kDa

Molecular Weight(Observed): N/A