INK-128 | 9527

INK-128 is a potent, selective and ATP-competituve mTORC1/2 inhibitor with potential anticancer properties. Displays >200-fold less selectivity towards class I PI3-K isoforms. Recently, it has been shown that INK-128 can also suppress HIV-1 in humanized mice.

INK-128 is a potent, selective and ATP-competituve mTORC1/2 inhibitor with potential anticancer properties. Displays >200-fold less selectivity towards class I PI3-K isoforms. Recently, it has been shown that INK-128 can also suppress HIV-1 in humanized mice.

9527 | INK-128 DataSheet

Alternate Name/Synonyms: 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; Sapanisertib; MLN0128

Appearance: Off-white solid

Formulation: N/A

CAS Number: 1224844-38-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₅H₁₅N₇O

Molecular Weight: 309.33

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>30 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent mTOR inhibitor

MDL Number: MFCD22124893

PubChem CID: 45375953

SMILES: CC(C)N1C2=C(C(=N1)C3=CC4=C(C=C3)OC(=N4)N)C(=NC=N2)N

InChi: InChI=1S/C15H15N7O/c1-7(2)22-14-11(13(16)18-6-19-14)12(21-22)8-3-4-10-9(5-8)20-15(17)23-10/h3-7H,1-2H3,(H2,17,20)(H2,16,18,19)

InChi Key: GYLDXIAOMVERTK-UHFFFAOYSA-N