INPP5J polyclonal Antibody | BS8311

INPP5J polyclonal Antibody | BS8311 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC IF

Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:10 - 1:100

Background: Inositol and phosphatidylinositol phosphates are important for numerous cellular processes, including neuronal survival and signal transductions from growth factors, neurotransmitters and G protein coupled receptors. INPP5J (inositol polyphosphate-5-phosphatase J), also known as phosphatidylinositol 4,5-bisphosphate 5-phosphatase A, PIPP (proline-rich inositol polyphosphate 5-phosphatase), PIB5PA or INPP5, is a 1,006 amino acid cytoplasmic protein that assists in the conversion of inositol 1,4-bisphosphate from inositol 1,4,5-trisphosphate. Expressed in lung, stomach, kidney, brain, small intestine and heart, INPP5J localizes to membrane ruffles, where it may also participate in modulating inositol and phosphatidylinositol polyphosphate-binding proteins. Encoded by a gene located on human chromosome 22, INPP5J undergoes alternative splicing to produce three isoforms.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: INPP5J polyclonal Antibody detects endogenous levels of INPP5J protein.

Molecular Weight: ~ 107 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A; Inositol polyphosphate 5-phosphatase J; INPP5J; PIB5PA; PIPP

Immunogen: Recombinant full length Human INPP5J.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Toll-like Receptor signaling,