INPPL1 Antibody | 13-439

INPPL1 Antibody | 13-439 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 100-310 of human INPPL1 (NP_001558.3) .

Research Area: Cancer, Cell Cycle, Growth Factors, Immunology, Neuroscience, Signal Transduction

Tested Application: WB

Application: WB: 1:500 - 1:2000

Specificiy: N/A

Positive Control 1: HeLa

Positive Control 2: U-251MG

Positive Control 3: A-549

Positive Control 4: BT-474

Positive Control 5: Mouse heart

Positive Control 6: Mouse brain

Molecular Weight: Observed: 160kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: OPSMD, SHIP2, phosphatidylinositol 3, 4, 5-trisphosphate 5-phosphatase 2, 51C protein, INPPL-1, SH2 domain-containing inositol-5'-phosphatase 2, SHIP-2, protein 51C

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.