INTS10 polyclonal Antibody | BS8312

INTS10 polyclonal Antibody | BS8312 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB IF

Application Range: WB: 1:500~1:2000 IF: 1:50~1:200

Background: RNA polymerase II (Pol II) is an enzyme that is composed of twelve subunits and is responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, thereby allowing transcription to begin. The integrator complex is a multi-protein complex that associates with the C-terminal domain of Pol II and is involved in small nuclear RNA (snRNA) transcription and 3’-end processing. INTS10 (integrator complex subunit 10) is also known as INT10 and is a 710 amino acid protein that is localized to the nucleus. INTS10 is a component of the integrator complex and, as such, is thought to aid in the regulation of 3’-end processing of spliceosomal U1 and U2 snRNAs.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: INTS10 polyclonal Antibody detects endogenous levels of INTS10 protein.

Molecular Weight: ~ 70 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Integrator complex subunit 10; Int10; INTS10; C8orf35

Immunogen: Recombinant full length Human INTS10.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Nuclear Receptor Signaling,