INTS3 Antibody (Center) [APR33522G]

INTS3 Antibody (Center) [APR33522G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This INTS3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 518-551 amino acids from the Central region of human INTS3.

Cellular Localisation: Nucleus. Cytoplasm. Note=Localizes to nuclear foci following DNA damage

Molecular Weight: 118070

Clone: Polyclonal

Gene Name: INTS3

Gene ID: 65123

Function: Component of the Integrator (INT) complex. The Integrator complex is involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable) . Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267) .

Summary: N/A

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB, FC

Dilution: FC--1:25 WB--1:2000

Synonyms: Integrator complex subunit 3, Int3, SOSS complex subunit A, Sensor of single-strand DNA complex subunit A, SOSS-A, Sensor of ssDNA subunit A, INTS3, C1orf193, C1orf60