Ionomycin (Calcium salt) | 1566

Antibiotic that acts as a potent and selective calcium ionophore; more effective than A23187. Ionomycin binds Ca2+ in the 7.0-9.5 pH range with the resulting complex exhibiting intense UV absorption. Ionomycin induces apoptosis in immature B cell lines and in cultured embryonic rat cortical neurons. More mature B cell lines do not undergo apoptosis, but are arrested in the G1 phase of the cell cycle.

Ionomycin is a n antibiotic that acts as a potent and selective calcium ionophore; more effective than A23187. Ionomycin binds Ca2+ in the 7.0-9.5 pH range with the resulting complex exhibiting intense UV absorption.

1566 | Ionomycin (Calcium salt) DataSheet

Alternate Name/Synonyms:

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 56092-82-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₄₁H₇₀O₉.Ca²⁺

Molecular Weight: 747.1

Cell-Permeable?: Yes

Purity: ≥99%

Solubilities: DMSO

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A calcium ionophore

MDL Number: MFCD00083634

PubChem CID: 6446270

SMILES: CC(CCC(=O)[O-])CC(C)CC(C)C(=O)C=C(C(C)CC(C)CC=CC(C)C(C(C)C(CC1CCC(O1)(C)C2CCC(O2)(C)C(C)O)O)O)[O-].[Ca+2]

InChi: InChI=1S/C41H72O9.Ca/c1-25(21-29(5)34(43)24-35(44)30(6)22-27(3)20-26(2)14-15-38(46)47)12-11-13-28(4)39(48)31(7)36(45)23-33-16-18-41(10,49-33)37-17-19-40(9,50-37)32(8)42;/h11,13,24-33,36-37,39,42-43,45,48H,12,14-23H2,1-10H3,(H,46,47);/q;+2/p-2/b13-11+,34-24-;/t25-,26-,27+,28-,29-,30+,31+,32-,33+,36+,37-,39-,40+,41+;/m1./s1

InChi Key: WKRWUYKLUMMAKG-WYGBAUISSA-L