IP3 Receptor polyclonal Antibody | BS90732

IP3 Receptor polyclonal Antibody | BS90732 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB IHC FC

Application Range: WB:1:500-1:1,000 IHC:1:50-1:200 FC:1:50-1:100

Background: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: IP3 Receptor polyclonal Antibody detects endogenous levels of IP3 Receptor protein.

Molecular Weight: 314 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: IP3R 1, InsP3R1, Type 1 InsP3 receptor, ITPR1, INSP3R1, 4, 5-trisphosphate receptor, 5-trisphosphate receptor type 1, DKFZp313E1334, DKFZp313N1434, inositol 1 4 5 triphosphate receptor type 1, Inositol 1 4 5 trisphosphate Receptor Type 1, Inositol 1, InsP3R1, IP3, IP3 receptor, IP3 receptor isoform 1, IP3R 1, IP3R, IP3R1, ITPR 1, Itpr1, ITPR1, SCA15, SCA16, SCA29, Type 1 inositol 1 4 5 trisphosphate receptor, Type 1 inositol 1, Type 1 InsP3 receptor,

Immunogen: Synthetic peptide within C-terminal human IP3 Receptor.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Peptide affinity purified.

Pathway: