IQGAP1 monoclonal Antibody | MB63646

IQGAP1 monoclonal Antibody | MB63646 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: IHC, WB

Application Range: WB 1:500, IHC 1:5000

Background: This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: IQ motif containing GTPase activating protein 1

Molecular Weight: 189.1 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: HUMORFA01; p195; SAR1

Immunogen: Human recombinant protein fragment corresponding to amino acids 464-609 of human IQGAP1 (NP_003861) produced in E.coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A