Description
Members of the Interferon regulatory factor (IRF) family regulate gene expression critical to immune response, hemopoiesis, and proliferation. IRF-3 is a member of the IRF family, and is distinct from other family members. Its transcriptional activity is regulated solely by posttranslational modifications. It plays a crucial role in activation of innate immunity and inflammation in response to viral infection. Recombinant human IRF3 was expressed in E.coli and purified by using conventional chromatography techniques.
7323 | IRF3 human recombinant DataSheet
Biomolecule/Target: IRF3
Synonyms: Interferon regulatory factor-3
Alternates names: Interferon regulatory factor-3
Taglines: Plays a crucial role in activation of innate immunity and inflammation in response to viral infection
NCBI Gene ID #: 50706
NCBI Gene Symbol: POSTN
Gene Source: Human
Accession #: Q62009
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 95%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: < 1.0 EU per 1 microgram of protein
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 13 kDa (112 aa, 1-112 aa), confirmed by MALDI-TOF.
Concentration: 1 mg/ml
Appearance: Liquid
Physical form description: 1 mg/ml in Phosphate-buffered saline (pH 7.4).
Reconstitution Instructions: N/A
Amino acid sequence: MGTPKPRILP WLVSQLDLGQ LEGVAWVNKS RTRFRIPWKH GLRQDAQQED FGIFQAWAEA TGAYVPGRDK PDLPTWKRNF RSALNRKEGL RLAEDRSKDP HDPHKIYEFV NS