Description
IRS 1 (Ab 639) Antibody | 79-589 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse
Homology: N/A
Immunogen: IRS-1 (Ab-639) antibody was raised against a peptide sequence around aa.637~641 (P-K-S-V-S) derived from Human IRS-1.
Research Area: Other
Tested Application: WB, IF
Application: Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200
Specificiy: This antibody detects endogenous level of total IRS-1 protein.
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 180 kDa
Validation: N/A
Isoform: N/A
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality: Polyclonal
Clone: N/A
Isotype: N/A
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+) , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Condition: Store antibody at -20˚C for up to one year.
Alternate Name: HIRS-1, MAPTL, MTBT1, TAU, IRS-1, IRS1
User Note: N/A
BACKGROUND: May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit