ISCU Polyclonal Antibody | E-AB-18785

ISCU Polyclonal Antibody | E-AB-18785 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 2310020H20Rik, HML, hnifU, Iron sulfur cluster assembly enzyme ISCU mitochondrial, Iron sulfur cluster scaffold homolog (E. coli), Iron sulfur cluster scaffold homolog, Iron-sulfur cluster assembly enzyme ISCU, Iscu, IscU iron sulfur cluster scaffold homolog, ISCU, ISU2, MGC74517, mitochondrial, NIFU, NifU like N terminal domain containing, NifU like N terminal domain containing protein, NifU like protein, NifU-like N-terminal domain-containing protein, NifU-like protein, NIFUN, Nitrogen fixation cluster like, OTTHUMP00000238760, OTTHUMP00000238761, OTTHUMP00000238762, OTTHUMP00000238764, OTTHUMP00000238765

Application: WB, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Metabolism, Signal transduction

Background: This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response. Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion. Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis. A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein. A pseudogene of this gene is present on chromosome 1.

Concentration: 0.96 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human ISCU

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 18 kDa

Molecular Weight(Observed): Refer to figures