Description
ISCU Polyclonal Antibody | E-AB-18785 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: 2310020H20Rik, HML, hnifU, Iron sulfur cluster assembly enzyme ISCU mitochondrial, Iron sulfur cluster scaffold homolog (E. coli), Iron sulfur cluster scaffold homolog, Iron-sulfur cluster assembly enzyme ISCU, Iscu, IscU iron sulfur cluster scaffold homolog, ISCU, ISU2, MGC74517, mitochondrial, NIFU, NifU like N terminal domain containing, NifU like N terminal domain containing protein, NifU like protein, NifU-like N-terminal domain-containing protein, NifU-like protein, NIFUN, Nitrogen fixation cluster like, OTTHUMP00000238760, OTTHUMP00000238761, OTTHUMP00000238762, OTTHUMP00000238764, OTTHUMP00000238765
Application: WB, ELISA
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Metabolism, Signal transduction
Background: This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response. Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion. Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis. A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein. A pseudogene of this gene is present on chromosome 1.
Concentration: 0.96 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Fusion protein of human ISCU
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 18 kDa
Molecular Weight(Observed): Refer to figures