LBD
ISG20 Antibody (Center) [APR04121G]
- SKU:
- LBD-APR04121G
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- Usually ships in 5 working days
Description
ISG20 Antibody (Center) [APR04121G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This ISG20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the Central region of human ISG20.
Cellular Localisation: Nucleus. Nucleus, nucleolus. Cytoplasm. Nucleus, Cajal body
Molecular Weight: 20363
Clone: Polyclonal
Gene Name: ISG20
Gene ID: 3669
Function: Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and also has minor activity towards single-stranded DNA. Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV), hepatitis A virus (HAV) and yellow fever virus (YFV) in an exonuclease-dependent manner. May also play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis.
Summary: Tissue Location: Highly expressed in peripheral blood leukocytes, spleen, thymus, colon and lung. Up regulated by E2 in estrogen receptor-positive breast cancer lines.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Interferon-stimulated gene 20 kDa protein, Estrogen-regulated transcript 45 protein, Promyelocytic leukemia nuclear body-associated protein ISG20, ISG20, HEM45