Isradipine | 2564

Cell-permeable. A potent and selective voltage-gated L-type calcium channel blocker. Displays antiatherosclerotic effects and improves endothelium-mediated nitric oxide-dependent vasodilation. Displays neuroprotective activity in rat models.

Isradipine is a potent and selective voltage-gated L-type calcium channel blocker. Displays antiatherosclerotic effects and improves endothelium-mediated nitric oxide-dependent vasodilation. Displays neuroprotective activity in rat models.

2564 | Isradipine DataSheet

Alternate Name/Synonyms: 4-(4-Benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid, methyl, 1-methylester diester

Appearance: Yellow solid

Formulation: N/A

CAS Number: 75695-93-1

Structure Available?: Y

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₉H₂₁N₃O₅

Molecular Weight: 371.4

Cell-Permeable?: Yes

Purity: ≥98% by TLC

Solubilities: DMSO (~25 mg/ml) or EtOH (~ 15 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: Avoltage-gated L-type calcium channel blocker

MDL Number: MFCD00153820

PubChem CID: 3784

SMILES: CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC=CC3=NON=C32)C(=O)OC

InChi: InChI=1S/C19H21N3O5/c1-9(2)26-19(24)15-11(4)20-10(3)14(18(23)25-5)16(15)12-7-6-8-13-17(12)22-27-21-13/h6-9,16,20H,1-5H3

InChi Key: HMJIYCCIJYRONP-UHFFFAOYSA-N