Description
ISX9 promotes neurogenesis in vivo enhancing the proliferation and differentiation of hippocampal subgranular zone neuroblasts and enhances memory. Induces robust neuronal differentiation in adult neural stem cells. Increases insulin production by pancreatic β cells. Blocks malignant astrocyte proliferation, downregulates their astrocyte character, induces reentry into the cell cycle and upregulates neuronal gene expression.
ISX9 promotes neurogenesis in vivo enhancing the proliferation and differentiation of hippocampal subgranular zone neuroblasts and enhances memory. Induces robust neuronal differentiation in adult neural stem cells. Increases insulin production by pancreatic β cells. Blocks malignant astrocyte proliferation, downregulates their astrocyte character, induces reentry into the cell cycle and upregulates neuronal gene expression.
Alternate Name/Synonyms: N-cyclopropyl-5-(2-thienyl)-3-isoxazolecarboxamide
Appearance: Beige solid
Formulation: N/A
CAS Number: 832115-62-5
Structure Available?: Y
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₁H₁₀N₂O₂S
Molecular Weight: 234.28
Cell-Permeable?: Yes
Purity: ≥98% by TLC
Solubilities: DMSO (~60 mg/ml) or EtOH (~ 15 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A neurogenic differentiation inducer
MDL Number: N/A
PubChem CID: N/A
SMILES: O=C(NC1CC1)C2=NOC(C3=CC=CS3)=C2
InChi: InChI=1S/C11H10N2O2S/c14-11(12-7-3-4-7)8-6-9(15-13-8)10-2-1-5-16-10/h1-2,5-7H,3-4H2,(H,12,14)
InChi Key: SYENTKHGMVKGAQ-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
24 months |