ISX9 | 2563

ISX9 promotes neurogenesis in vivo enhancing the proliferation and differentiation of hippocampal subgranular zone neuroblasts and enhances memory. Induces robust neuronal differentiation in adult neural stem cells. Increases insulin production by pancreatic β cells. Blocks malignant astrocyte proliferation, downregulates their astrocyte character, induces reentry into the cell cycle and upregulates neuronal gene expression.

ISX9 promotes neurogenesis in vivo enhancing the proliferation and differentiation of hippocampal subgranular zone neuroblasts and enhances memory. Induces robust neuronal differentiation in adult neural stem cells. Increases insulin production by pancreatic β cells. Blocks malignant astrocyte proliferation, downregulates their astrocyte character, induces reentry into the cell cycle and upregulates neuronal gene expression.

2563 | ISX9 DataSheet

Alternate Name/Synonyms: N-cyclopropyl-5-(2-thienyl)-3-isoxazolecarboxamide

Appearance: Beige solid

Formulation: N/A

CAS Number: 832115-62-5

Structure Available?: Y

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₁H₁₀N₂O₂S

Molecular Weight: 234.28

Cell-Permeable?: Yes

Purity: ≥98% by TLC

Solubilities: DMSO (~60 mg/ml) or EtOH (~ 15 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A neurogenic differentiation inducer

MDL Number: N/A

PubChem CID: N/A

SMILES: O=C(NC1CC1)C2=NOC(C3=CC=CS3)=C2

InChi: InChI=1S/C11H10N2O2S/c14-11(12-7-3-4-7)8-6-9(15-13-8)10-2-1-5-16-10/h1-2,5-7H,3-4H2,(H,12,14)

InChi Key: SYENTKHGMVKGAQ-UHFFFAOYSA-N