Itaconic acid | 2576

An inhibitor of isocitrate lyase, the key enzyme of the glyoxylate cycle, essential for bacterial growth. Inhibits the growth of bacteria expressing isocitrate lyase. A phosphofructokinase (PFKII) inhibitor. Suppresses glycolysis by decreasing the level of fructose 2,6-bisphosphate, resulting in decreased visceral fat. Might be involved in the regulation of metabolism.

Itaconic acid is an inhibitor of isocitrate lyase, the key enzyme of the glyoxylate cycle, essential for bacterial growth. Inhibits the growth of bacteria expressing isocitrate lyase. A phosphofructokinase (PFKII) inhibitor. Suppresses glycolysis by decreasing the level of fructose 2,6-bisphosphate, resulting in decreased visceral fat. Might be involved in the regulation of metabolism.

2576 | Itaconic acid DataSheet

Alternate Name/Synonyms: Methylenesuccinic acid; 2-Propene-1,2-dicarboxylic acid

Appearance: White solid

Formulation: N/A

CAS Number: 97-65-4

Structure Available?: Y

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₅H₆O₄

Molecular Weight: 130.1

Cell-Permeable?: No

Purity: ≥99% by titration

Solubilities: H₂O or EtOH

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: An isocitrate lyase inhibitor

MDL Number: MFCD00004260

PubChem CID: 811

SMILES: C=C(CC(=O)O)C(=O)O

InChi: InChI=1S/C5H6O4/c1-3(5(8)9)2-4(6)7/h1-2H2,(H,6,7)(H,8,9)

InChi Key: LVHBHZANLOWSRM-UHFFFAOYSA-N