ITGAV Polyclonal Antibody | E-AB-70152

ITGAV Polyclonal Antibody | E-AB-70152 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: antigen identified by monoclonal L230, CD 51, CD51, DKFZp686A08142, Integrin alpha five, integrin alpha V beta 3, Integrin alpha-5, integrin alpha-V, Integrin alpha-V light chain, integrin alphaVbeta3, integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51), ITAV, ITGAV, MSK 8, Msk8, Vitronectin receptor subunit alpha, VNRA, VTNR

Application: WB

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cardiovascular, Microbiology, Stem Cells

Background: The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

Concentration: 0.76 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Integrin alpha-V

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:1000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 116 kDa

Molecular Weight(Observed): 130 kDa