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Ivabradine Hydrochloride | B1595

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SKU:
26-B1595-GEN
Availability:
Usually shipped in 5 working days
£644.00

Description

Ivabradine hydrochloride is a highly selective open channel blocker that targets the mixed Na⁺/K⁺ inward “funny current” (If) carried by hyperpolarization-activated cyclic nucleotide gated (HCN) channels. It has antianginal activity. It lowers heart rate and reduces myocardial oxygen demand.

Ivabradine hydrochloride is a highly selective open channel blocker that targets the mixed Na⁺/K⁺ inward “funny current” (If) carried by hyperpolarization-activated cyclic nucleotide gated (HCN) channels. It has antianginal activity. It lowers heart rate and reduces myocardial oxygen demand.

B1595 | Ivabradine Hydrochloride DataSheet

Alternate Name/Synonyms: 3-[3-[[[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one, monohydrochloride

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 148849-67-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₂₇H₃₆N₂O₅·HCl

Molecular Weight: 505.1

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: H₂O (~ 5mg/ml on warming)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A highly selective open channel blocker

MDL Number: MFCD00929899

PubChem CID: 3045381

SMILES: CN(CCCN1CCC2=CC(=C(C=C2CC1=O)OC)OC)CC3CC4=CC(=C(C=C34)OC)OC.Cl

InChi: InChI=1S/C27H36N2O5.ClH/c1-28(17-21-11-20-14-25(33-4)26(34-5)16-22(20)21)8-6-9-29-10-7-18-12-23(31-2)24(32-3)13-19(18)15-27(29)30;/h12-14,16,21H,6-11,15,17H2,1-5H3;1H/t21-;/m1./s1

InChi Key: HLUKNZUABFFNQS-ZMBIFBSDSA-N

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Additional Information

Storage Condition:
-20°C
Shipping Condition:
Gel Pack
Shelf Life:
36 months
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