Description
IVD Antibody | 15-959 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 33-200 of human IVD (NP_002216.2) .
Research Area: Cancer, Signal Transduction
Tested Application: WB, IHC
Application: WB: 1:200 - 1:2000
IHC: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: MCF7
Positive Control 2: Mouse heart
Positive Control 3: Mouse kidney
Positive Control 4: Mouse liver
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 42kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: ACAD2, isovaleryl-CoA dehydrogenase, mitochondrial, epididymis secretory sperm binding protein, isovaleryl Coenzyme A dehydrogenase
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.