IVD, Human Recombinant | P1577

IVD (Isovaleryl Coenzyme A dehydrogenase) is a mitochondrial matrix enzyme that belongs to the acyl-CoA dehydrogenase family. IVD is a homotetrameric flavoenzyme which catalyzes the conversion of isovaleryl-CoA to 3-methylcrotonyl-CoA. Defects of the IVD gene lead to ineffective isoforms that are the underlying cause of isovaleric acidemia. Recombinant human IVD protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

P1577 | IVD, Human Recombinant DataSheet

Biomolecule/Target :

Synonyms: Isovaleryl-CoA dehydrogenase mitochondrial, ACAD2

Alternates names: Isovaleryl-CoA dehydrogenase mitochondrial, ACAD2

Taglines: Flavoenzyme which catalyzes the conversion of isovaleryl-CoA to 3-methylcrotonyl-CoA

NCBI Gene ID #: 3712

NCBI Gene Symbol: IVD

Gene Source: Human

Accession #: P26440

Recombinant: TRUE

Source: E. coli

Purity by SDS-PAGE: >90%

Assay: SDS - PAGE

Purity:

Assay #2:

Endotoxin Level:

Activity (Specifications/test method):

Biological activity:

Results:

Binding Capacity:

Unit Definition:

Molecular Weight: 45.3 kDa (415aa) (N-terminal His- Tag)

Concentration:

Appearance: Liquid

Physical form description: In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 10% glycerol

Reconstitution Instructions:

Amino acid sequence: aa 33-426

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans