JAG1 monoclonal Antibody | MB63679

JAG1 monoclonal Antibody | MB63679 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: IHC, WB

Application Range: WB 1:2000, IHC 1:150

Background: The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: jagged 1

Molecular Weight: 133.6 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: AGS; AHD; AWS; CD339; HJ1; JAGL1

Immunogen: Human recombinant protein fragment corresponding to amino acids 523-759 of human JAG1 (NP_000205) produced in E.coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A