JAK3 Polyclonal Antibody | E-AB-31846

JAK3 Polyclonal Antibody | E-AB-31846 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: EC 2.7.10.2, JAK 3, JAK L, JAK-3, Jak3, JAK3 HUMAN, JAK3, JAKL, Janus kinase 3 (a protein tyrosine kinase, leukocyte), Janus kinase 3, Janus Kinase3, L JAK, L-JAK, Leukocyte janus kinase, LJAK, Protein tyrosine kinase leukocyte, Tyrosine protein kinase JAK3, Tyrosine-protein kinase JAK3

Application: WB, IHC-p, IF, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Background: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthesized peptide derived from human JAK3 around the non-phosphorylation site of Tyr785.

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 125 kDa

Molecular Weight(Observed): 125 kDa