26
Jasplakinolide, jaspis johnstoni | 1689
- SKU:
- 26-1689-GEN
- Availability:
- Usually shipped in 5 working days
Description
A cell- permeable, non-fluorescent F-actin probe. Displays antifungal and antitumor properties. A potent inducer of actin polymerization and stabilization, Jasplakinolide competes with phallotoxins for actin binding (Kd = 15 nM). It also enhances apoptosis induced by IL-2 deprivation.
Jasplakinolide is a cell- permeable, non-fluorescent F-actin probe. A potent inducer of actin polymerization and stabilization, Jasplakinolide competes with phallotoxins for actin binding (Kd = 15 nM). It also enhances apoptosis induced by IL-2 deprivation.
1689 | Jasplakinolide, jaspis johnstoni DataSheet
Alternate Name/Synonyms:
Appearance: Off-white to yellow solid
Formulation: N/A
CAS Number: 102396-24-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₃₆H₄₅BrN₄O₆
Molecular Weight: 709.67
Cell-Permeable?: Yes
Purity: ≥95% by HPLC
Solubilities: DMSO or MeOH
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A non-fluorescent F-actin probe
MDL Number: MFCD00873735
PubChem CID: 6436289
SMILES: CC1CC(OC(=O)CC(NC(=O)C(N(C(=O)C(NC(=O)C(CC(=C1)C)C)C)C)CC2=C(NC3=CC=CC=C32)Br)C4=CC=C(C=C4)O)C
InChi: InChI=1S/C36H45BrN4O6/c1-20-15-21(2)17-23(4)47-32(43)19-30(25-11-13-26(42)14-12-25)40-35(45)31(18-28-27-9-7-8-10-29(27)39-33(28)37)41(6)36(46)24(5)38-34(44)22(3)16-20/h7-15,21-24,30-31,39,42H,16-19H2,1-6H3,(H,38,44)(H,40,45)/b20-15+/t21-,22+,23-,24-,30+,31+/m0/s1
InChi Key: GQWYWHOHRVVHAP-HZIRKPFGSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
24 months |