Jatrorrhizine | 2530

Jatrorrhizine is a a novel tetrahydroisoquinoline alkaloid originally extracted from the Chinese herb coptidis rhizome. Protects neuronal-like cells against H₂O₂-induced toxicity. JAT also displays neuroprotective effects against Aβ₂₅₋₃₅-induced injury via its antioxidative potential. Potential therapeutic for gastrointestinal disorders.

Jatrorrhizine is a a novel tetrahydroisoquinoline alkaloid originally extracted from the Chinese herb coptidis rhizome. Protects neuronal-like cells against H₂O₂-induced toxicity. JAT also displays neuroprotective effects against Aβ₂₅₋₃₅-induced injury via its antioxidative potential. Potential therapeutic for gastrointestinal disorders.

2530 | Jatrorrhizine DataSheet

Alternate Name/Synonyms: 7,8,13,13α-Tetradehydro-3-hydroxy-2,9,10-trimethoxyberbinium, Neprotin, Yatrorizine

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 3621-38-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₀H₂₀NO₄

Molecular Weight: 338.38

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A neuroprotective agent

MDL Number: N/A

PubChem CID: 72323

SMILES: COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)O)OC)OC

InChi: InChI=1S/C20H19NO4/c1-23-18-5-4-12-8-16-14-10-19(24-2)17(22)9-13(14)6-7-21(16)11-15(12)20(18)25-3/h4-5,8-11H,6-7H2,1-3H3/p+1

InChi Key: MXTLAHSTUOXGQF-UHFFFAOYSA-O