Description
Jatrorrhizine is a a novel tetrahydroisoquinoline alkaloid originally extracted from the Chinese herb coptidis rhizome. Protects neuronal-like cells against H₂O₂-induced toxicity. JAT also displays neuroprotective effects against Aβ₂₅₋₃₅-induced injury via its antioxidative potential. Potential therapeutic for gastrointestinal disorders.
Jatrorrhizine is a a novel tetrahydroisoquinoline alkaloid originally extracted from the Chinese herb coptidis rhizome. Protects neuronal-like cells against H₂O₂-induced toxicity. JAT also displays neuroprotective effects against Aβ₂₅₋₃₅-induced injury via its antioxidative potential. Potential therapeutic for gastrointestinal disorders.
2530 | Jatrorrhizine DataSheet
Alternate Name/Synonyms: 7,8,13,13α-Tetradehydro-3-hydroxy-2,9,10-trimethoxyberbinium, Neprotin, Yatrorizine
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 3621-38-3
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₀H₂₀NO₄
Molecular Weight: 338.38
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A neuroprotective agent
MDL Number: N/A
PubChem CID: 72323
SMILES: COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)O)OC)OC
InChi: InChI=1S/C20H19NO4/c1-23-18-5-4-12-8-16-14-10-19(24-2)17(22)9-13(14)6-7-21(16)11-15(12)20(18)25-3/h4-5,8-11H,6-7H2,1-3H3/p+1
InChi Key: MXTLAHSTUOXGQF-UHFFFAOYSA-O
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
24 months |