Description
JNJ-27018966 is an orally active μ- and κ-opioid receptor agonist and δ-opioid receptor antagonist, with powerful antidiarrheal and analgesic activity. It is believed to act locally in the enteric nervous system, and has no adverse effects in the central nervous system.
JNJ-27018966 is an orally active μ- and κ-opioid receptor agonist and δ-opioid receptor antagonist, with powerful antidiarrheal and analgesic activity. It is believed to act locally in the enteric nervous system, and has no adverse effects in the central nervous system.
B1109 | JNJ-27018966 DataSheet
Alternate Name/Synonyms: 5-(((S)-2-amino-3-(4-carbamoyl-2,6-dimethylphenyl)-N-((S)-1-(5-phenyl-1H-imidazol-2-yl)ethyl)propanamido)methyl)-2-methoxybenzoic acid; Eluxadoline; Viberzi
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 864821-90-9
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₃₂H₃₅N₅O₅
Molecular Weight: 569.66
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A μ- and κ-opioid receptor agonist and δ-opioid receptor antagonist
MDL Number: N/A
PubChem CID: 11250029
SMILES: CC1=CC(=CC(=C1CC(C(=O)N(CC2=CC(=C(C=C2)OC)C(=O)O)C(C)C3=NC=C(N3)C4=CC=CC=C4)N)C)C(=O)N
InChi: InChI=1S/C32H35N5O5/c1-18-12-23(29(34)38)13-19(2)24(18)15-26(33)31(39)37(17-21-10-11-28(42-4)25(14-21)32(40)41)20(3)30-35-16-27(36-30)22-8-6-5-7-9-22/h5-14,16,20,26H,15,17,33H2,1-4H3,(H2,34,38)(H,35,36)(H,40,41)/t20-,26-/m0/s1
InChi Key: QFNHIDANIVGXPE-FNZWTVRRSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |