JTV1 polyclonal Antibody | AP6009

JTV1 polyclonal Antibody | AP6009 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: JTV1, also known as P38 or AIMP2 (aminoacyl tRNA synthetase complex-interacting multifunctional protein 2), is a 320 amino acid nuclear and cytoplasmic protein that is a component of the aminoacyl-tRNA synthase complex. Containing one GST C-terminal domain, JTV1 mediates ubiquitination and degradation of FBP1, a transcriptional activator of c-Myc, leading to c-Myc down-regulation, which is required for aveolar type II cell differentiation. JTV1 also participates in blocking MDM2-mediated ubiquitination, degradation of p53 and functions as a proapoptotic factor.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: JTV1 polyclonal Antibody detects endogenous levels of JTV1 protein.

Molecular Weight: ~ 35 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Aminoacyl tRNA synthase complex-interacting multifunctional protein 2; Multisynthase complex auxiliary component p38; Protein JTV-1; AIMP2; JTV1; PRO0992

Immunogen: Recombinant full length Human JTV1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: