Kallikrein-2, Human Recombinant | P1579

KLK2 is a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. KLK2 is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. Recombinant human KLK2 protein, fused to His-tag at N-terminus, was expressed in E. coli.

P1579 | Kallikrein-2, Human Recombinant DataSheet

Biomolecule/Target :

Synonyms: Glandular kallikrein-1, hGK-1, Tissue kallikrein-2

Alternates names: Glandular kallikrein-1, hGK-1, Tissue kallikrein-2

Taglines: Trypsin-like serine protease that selectively cleaves at arginine residues

NCBI Gene ID #: 3817

NCBI Gene Symbol: KLK2

Gene Source: Human

Accession #: P20151

Recombinant: TRUE

Source: E. coli

Purity by SDS-PAGE: >85%

Assay: SDS - PAGE

Purity:

Assay #2:

Endotoxin Level:

Activity (Specifications/test method):

Biological activity:

Results:

Binding Capacity:

Unit Definition:

Molecular Weight: 28.5 kDa (260aa) (N-terminus His-Tag)

Concentration:

Appearance: Liquid

Physical form description: In 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M urea, 10% glycerol

Reconstitution Instructions:

Amino acid sequence: aa 25-261

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans