26
Kallikrein-2, Human Recombinant | P1579
- SKU:
- 26-P1579-GEN
- Availability:
- Usually shipped in 5 working days
Description
KLK2 is a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. KLK2 is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. Recombinant human KLK2 protein, fused to His-tag at N-terminus, was expressed in E. coli.
P1579 | Kallikrein-2, Human Recombinant DataSheet
Biomolecule/Target :
Synonyms: Glandular kallikrein-1, hGK-1, Tissue kallikrein-2
Alternates names: Glandular kallikrein-1, hGK-1, Tissue kallikrein-2
Taglines: Trypsin-like serine protease that selectively cleaves at arginine residues
NCBI Gene ID #: 3817
NCBI Gene Symbol: KLK2
Gene Source: Human
Accession #: P20151
Recombinant: TRUE
Source: E. coli
Purity by SDS-PAGE: >85%
Assay: SDS - PAGE
Purity:
Assay #2:
Endotoxin Level:
Activity (Specifications/test method):
Biological activity:
Results:
Binding Capacity:
Unit Definition:
Molecular Weight: 28.5 kDa (260aa) (N-terminus His-Tag)
Concentration:
Appearance: Liquid
Physical form description: In 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M urea, 10% glycerol
Reconstitution Instructions:
Amino acid sequence: aa 25-261
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans
Additional Information
Storage Temperature: |
-20°C |
Shipping: |
Gel Pack |
Shelf Life: |
12 months |