KANK3 Antibody | 7311

KANK3 Antibody | 7311 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: KANK3 antibody was raised against an 18 amino acid peptide near the amino terminus of human KANK3 .
The immunogen is located within amino acids 50 - 100 of KANK3.

Research Area: Cancer, Cell Cycle

Tested Application: E, WB, IHC-P

Application: KANK3 Antibody can be used for detection of KANK3 by Western blot starting at 1 μg/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Specificiy: Two alternatively spliced transcript variants encoding different isoforms have been identified.

Positive Control 1: Cat. No. 1202 - A431 Cell Lysate

Positive Control 2: Cat. No. 10-401 - Human Kidney Tissue Slide

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 90 kDa
Observed: 100 kDa

Validation: N/A

Isoform: N/A

Purification: KANK3 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: KANK3 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: KANK3 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: KANK3 Antibody: ANKRD47, ANKRD47, KN motif and ankyrin repeat domain-containing protein 3, Ankyrin repeat domain-containing protein 47

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: KANK3 Antibody: Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. Like other members of the KANK family, KANK3 (KN motif and ankyrin repeat domain-containing protein 3) , is thought to play a role in the formation of actin stress fibers. In zebrafish, the homolog of KANK3 interacts with the adaptor protein Numb, a protein implicated in multiple basic cellular processes, and is essential for epidermal integrity and neurulation, suggesting that KANK3 may play a similar role in higher organisms.