Kartogenin | 2066

Cell-permeable. Kartogenin promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes (EC₅₀ = 100 nM). Displays chondroprotective effects in vitro and is efficacious in two animal models of osteoarthritis.

Kartogenin promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes (EC₅₀ = 100 nM). Displays chondroprotective effects in vitro and is efficacious in two animal models of osteoarthritis.

2066 | Kartogenin DataSheet

Alternate Name/Synonyms: 2-([1,1'-biphenyl]-4-ylcarbamoyl)benzoic acid

Appearance: White solid

Formulation: N/A

CAS Number: 4727-31-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₂₀H₁₅NO₃

Molecular Weight: 317.34

Cell-Permeable?: Yes

Purity: ≥99% by TLC

Solubilities: DMSO (~ 60 mg/ml) or EtOH (~ 14 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A stem cell differentiating agent

MDL Number: MFCD00560510

PubChem CID: 2826191

SMILES: C1=CC=C(C=C1)C2=CC=C(C=C2)NC(=O)C3=CC=CC=C3C(=O)O

InChi: InChI=1S/C20H15NO3/c22-19(17-8-4-5-9-18(17)20(23)24)21-16-12-10-15(11-13-16)14-6-2-1-3-7-14/h1-13H,(H,21,22)(H,23,24)

InChi Key: SLUINPGXGFUMLL-UHFFFAOYSA-N