Description
Cell-permeable. Kartogenin promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes (EC₅₀ = 100 nM). Displays chondroprotective effects in vitro and is efficacious in two animal models of osteoarthritis.
Kartogenin promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes (EC₅₀ = 100 nM). Displays chondroprotective effects in vitro and is efficacious in two animal models of osteoarthritis.
Alternate Name/Synonyms: 2-([1,1'-biphenyl]-4-ylcarbamoyl)benzoic acid
Appearance: White solid
Formulation: N/A
CAS Number: 4727-31-5
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₂₀H₁₅NO₃
Molecular Weight: 317.34
Cell-Permeable?: Yes
Purity: ≥99% by TLC
Solubilities: DMSO (~ 60 mg/ml) or EtOH (~ 14 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A stem cell differentiating agent
MDL Number: MFCD00560510
PubChem CID: 2826191
SMILES: C1=CC=C(C=C1)C2=CC=C(C=C2)NC(=O)C3=CC=CC=C3C(=O)O
InChi: InChI=1S/C20H15NO3/c22-19(17-8-4-5-9-18(17)20(23)24)21-16-12-10-15(11-13-16)14-6-2-1-3-7-14/h1-13H,(H,21,22)(H,23,24)
InChi Key: SLUINPGXGFUMLL-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
24 months |