KCNA1 Polyclonal Antibody | E-AB-12529

KCNA1 Polyclonal Antibody | E-AB-12529 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: AEMK, EA1, Episodic ataxia with myokymia, HBK1, HUK1, Kca1 1, Kcna1, KCNA1, Kcpvd, KV1.1, MBK1, mceph, MGC124402, MGC126782, MGC138385, MK1, MK1, mouse, homolog of KV1.1, Potassium channel protein 1, Potassium voltage gated channel shaker related subfamily member 1, Potassium voltage gated channel subfamily A member 1, Potassium voltage gated channel, shaker related subfamily, member 1 (episodic ataxia with myokymia), Potassium voltage-gated channel subfamily A member 1, RBK1, RCK1, Shak, Shaker related subfamily member 1, Voltage gated potassium channel subunit Kv1.1, Voltage-gated K(+) channel HuKI, Voltage-gated potassium channel HBK1, Voltage-gated potassium channel subunit Kv1.1

Application: WB, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Neuroscience

Background: This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).

Concentration: 0.4 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human KCNA1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 56 kDa

Molecular Weight(Observed): N/A