KCNAB1/Kv beta 1 Polyclonal Antibody | BS65438

KCNAB1/Kv beta 1 Polyclonal Antibody | BS65438 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Rabbit,Sheep,

Application: WB,

Application Range: WB=1:500-2000

Background: Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. The KV gene family encodes more than 30 proteins that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming å subunits (KV), which include the KV1, KV2, KV3 and KV4 proteins, and accessory or KV-subunits that modify the gating properties of the coexpressed KV subunits. KV∫, also known as KCNAB1 (potassium voltage-gated channel, shaker-related subfamily, beta member 1), is a 419 amino acid accessory K+ channel protein that exists as three alternatively spliced isoforms and regulates the activity of the pore-forming å subunit. It is expressed in brain, with highest levels detected in caudate nucleus, hippocampus and thalamus.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: KCNAB1/Kv beta 1 Polyclonal Antibody detects endogenous levels of KCNAB1/Kv beta 1 protein.

Molecular Weight: 47 kD

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: hKvb3; hKvBeta3; K (+) channel subunit beta-1; KCAB1_HUMAN; KCNA1B; KCNAB1; KV-BETA-1; Kvb1.3; Voltage-gated potassium channel beta-1 subunit; Voltage-gated potassium channel subunit beta-1.

Immunogen: KLH conjugated synthetic peptide derived from human KCNAB1/Kv beta 1:131-230/419

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: